David A. Martin, MD

Acting Instructor of Medicine; Senior Fellow
University of Washington
Seattle, WA
David Martin received his MD from the University of Rochester School of Medicine in New York. He has contributed to several books, and authored articles appearing in Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Cell Biology.

Project title: Genetic and Molecular Analyses of DNases in the Immune Response to DNA in Systemic Lupus Erythematosus (SLE)

Dr Martin is researching the role of both endogenous DNA and the DNase family of nucleases in order to better understand the autoimmune responses seen in SLE.

Selected publications

  • Martin DA, Elkon KE. Autoantibodies make a U-turn: the toll hypothesis for autoantibody specificity. J Exp Med 2005;202:1465-9.
  • Martin DA, Elkon KE. Apoptosis. In: Wallace DJ, Hahn BH, eds. Dubois' Lupus Erythematosus, 7e. 2005 (in press).
  • Martin DA, Elkon KE. Cytoplasmic mammalian DNA stimulates myeloid dendritic cells to produce Type I interferons independently of MyD88 or TLR9. Accepted for publication, Arthritis and Rheumatism (2005).
  • Martin DA, Elkon KE. Mechanisms of apoptosis. Rheum Dis Clin North Am 2004;30:441-54, vii.

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